| The first few amino acids were discovered in the early 19th century. In 1806, French chemists Louis-Nicolas Vauquelin and Pierre Jean Robiquet isolated a compound in asparagus that was subsequently named asparagine, the first amino acid to be discovered.[20][21] Cystine was discovered in 1810,[22] although its monomer, cysteine, remained undiscovered until 1884.[21][23] Glycine and leucine were discovered in 1820.[24] Usage of the term amino acid in the English language is from 1898.[25] Proteins were found to yield amino acids after enzymatic digestion or acid hydrolysis. In 1902, Emil Fischer and Franz Hofmeister proposed that proteins are the result of the formation of bonds between the amino group of one amino acid with the carboxyl group of another, in a linear structure that Fischer termed peptide.[26] |
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